… , such as Cryptococcus neoformans, is their ability to adapt to … transcript degradation and
mRNA decay in host-temperature … its transcriptome, further impairing its stress responsiveness. …

… ) mRNA decay during oxidative stress from H2O2, but is completely dispensable for adaptation
to host temperature stress of 37C… of mRNA synthesis and mRNA decay, known as mRNA …

… by increased concentrations and incubation temperature. Together, these results indicate …
and mRNA decay that drastically affects the ability of the fungal pathogen to adapt to oxidative …

… degradation, and mRNA surveillance and decay (26, 32… of Gcn2 to the stress adaptations
we observed in C. … response to temperature is driven mainly by Ccr4-dependent mRNA decay, …

… Furthermore, cytokinesis in these mutants is impaired and … thermal stress temperature induces
a preponderant mRNA … cytokines, GXM also promotes the uncoupling activity of NF-κB to …

… and that, while Ccr4-mediated mRNA decay is not a prerequisite for Mpk1 activation, Ccr4
either directly or indirectly modulates Hog1 activation during host temperature adaptation. …

… normal mammalian body temperature (1). Imperative to this … ] was also used to uncouple
proton motive force from oxygen … The explanation that loss of Mrj1 impairs the ETC at …

… optimal growth temperature is 25–30C, it needs to adapt to … In particular, (1) proteasomal
degradation of aberrant proteins (… cell wall synthesis are associated with the pathogenicity of C. …

… , and body temperature induce the targeted degradation of … demonstrated that Cryptococcus
neoformans's successful … RNA modifications regulate mRNA stability, which affects a range …

… clearance in the lung and impairs pro-inflammatory immune … These mechanisms of
uncoupling the transcriptome and … of adaptation to human host temperatures, degrading certain …